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News articleYahoo Finance· December 31, 2025

Stock market today: Dow, S&P 500, Nasdaq post double-digit gains in 2025 as AI trade powers market once again

View original at finance.yahoo.com
Stock market today: Dow, S&P 500, Nasdaq post double-digit gains in 2025 as AI trade powers market once again Stocks fell slightly during the final trading session of an eventful 2025 that saw the S&P 500 clinch a third-straight double-digit gain and the Nasdaq rise more than 20% for the third year in a row…
Opening lines of the source · Yahoo Finance · short snapshot — read the full document at the original

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  • Technical indicators show bitcoin's downtrend remains in place but likely flipping to bullish in January 2026

    80% confidence
  • US domestic oil inventories are expected to continue building through 2026

    80% confidence
  • Brent crude oil price targets are in the $50s per barrel

    80% confidence
  • Brent crude oil price targets are in the $50s per barrel, with potential for a drop into the $30s or $40s per barrel if OPEC does not change course

    80% confidence
  • 2026's oil oversupply is pegged at a level of 3.8 million barrels per day

    80% confidence
  • Expect the outperformance to continue in the utility-scale renewables market, though sector expected to consolidate as projects and regulation become more complex

    80% confidence
  • Each shareholder will be given one token per whole share owned, with various rewards being made available to token holders periodically throughout the year that could include benefits or discounts tied to Trump Media products

    80% confidence
  • Every Wall Street forecaster tracked by Bloomberg is predicting that stocks will rally for a fourth consecutive year in 2026

    80% confidence
  • Expect the outperformance to continue in the utility-scale renewables market, though sector expected to consolidate as projects and regulation become more complex

    80% confidence

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Live from the substrate
What we're seeing
Q4 2026 Biopharma Catalyst Cluster: Late-Stage Readouts and Regulatory Milestones
October 2026 brings a dense run of Phase 3 wins (ALOFT-IPF, RESTORE-3), new data presentations (Roche, Bayer, Lilly, Vertex, Galderma) and regulatory steps (FDA acceptance of Roche's vamikibart BLA, Scholar Rock's EMA resubmission). The next big catalyst is the ivonescimab FDA PDUFA date on 2026-11-14. Obesity combination studies (REDEFINE 4, TOGETHER-PsO) and the 2027 Maritime-1 completion point to more catalysts ahead. QAIAx's speculative AI-linked trial claims (the QIII pilot, targeted for 2027) are an unrelated micro-cap sideshow with weak evidence, and have little in common with the large-cap pipeline news.
Our read on the data ›
Signals we're tracking
EPKINLY Regulatory-Clinical Success Cascade
High probability of expanded label indications, additional combination approvals, and competitive positioning strength in follicular lymphoma market. Predicts positive commercial uptake and potential accelerated review for related indications.
Patterns we're watching ›
Where sources disagree
ING Group
Both facts record the same metric (shares_outstanding) for ING Group at the identical observation date (2025-12-31). FACT A states 2,902,437,688 shares; FACT B states 2,902 million shares (2,902,000,000). The difference is 437,688 shares (~0.015%). This is a genuine value conflict, though the discrepancy appears to result from FACT B rounding to the nearest million while FACT A provides the precise count.
We flag conflicts openly ›
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